Cipol‐N Soft Capsules 50mg

Microemulsion formulation of Cyclosporine 50mg/cap

  • Category : Household
  • Availability : In Stock

Cipol-N is a pharmaceutical form of the active ingredient Cipol-N based on the microemulsion principle, which reduces the variability of pharmacokinetic parameters and provides dose linearity of Cipol-N exposure with a more consistent absorption profile and less influence from concomitant food intake. The formulation is a microemulsion preconcentrate, which in pharmacokinetics and clinical studies has demonstrated that the correlation between trough concentration and exposure to Cipol-N is much stronger when Cipol-N is given as Cipol-N, Cipol-N than when it is given as Cipol-N.

Cipol-N is a pharmaceutical form of the active ingredient Cipol-N based on the microemulsion principle, which reduces the variability of pharmacokinetic parameters and provides dose linearity of Cipol-N exposure with a more consistent absorption profile and less influence from concomitant food intake. The formulation is a microemulsion preconcentrate, which in pharmacokinetics and clinical studies has demonstrated that the correlation between trough concentration and exposure to Cipol-N is much stronger when Cipol-N is given as Cipol-N, Cipol-N than when it is given as Cipol-N.The formation of the microemulsion itself takes place in the presence of water, either in the form of a beverage or in the form of the gastric fluid.

This medication is used to prevent organ rejection in people who have received a liver, kidney, or heart transplant. It is usually used along with other medications to allow your new organ to function normally. Cyclosporine belongs to a class of drugs known as immunosuppressants. It works by slowing down your body's defense system (immune system) to prevent your body from rejecting a transplanted organ.Because of the risk of severe allergic reactions from intravenous cyclosporine, it should be used only in patients who are unable to take cyclosporine by mouth. Once you are able to take medications by mouth, you should be switched from this form of cyclosporine to either the capsules or oral solution.

Organic Transplantation

Preoperative

14-17.5 mg/kg/day 4-12 Hours before surgery in Two divided doses.

Postoperative

14-17.5mg/kg/day in Two divided dosesfor 1-12 wekks and then reduce gradually in accordance with boodlevels until a maintenance dose of 2-6mg/kg/day is attained. Dose should be adjusted, if CIPOL-N is simultaneously used with other immunosuppressant.

Bone Marrow Transplantation

Preoperative

Miantenance dose of 12.5mg/kg/day in Two divided doses should be continued for 3-6 days after transplantation and then the dose is gradually tapered out in 1 year.

Postoperative

12.5-15mg/kg/day in Two divided doses to be administereda day before surgery. Lower doses of CIPOL-N should be used to treat mild chroic GvHD.